Route 65

Route 65 (HYBRID)
THC 32.25%

Route 65 is a hybrid cannabis strain made from a genetic cross of Studio 54 X RS11 cannabis strains. Route 65 features a gassy terpene flavor profile. Route 65 produces effects that calming, relaxing, giggly, and talkative. The dominant terpene in Route 65 cannabis is Caryophyllene & Limonene.

Origins and Genetics of Route 65

Route 65 is the lovechild of two iconic strains—Studio 54, a glitzy and potent sativa-leaning hybrid, and RS11 (also known as Rainbow Sherbert #11), a flavorful indica-dominant hybrid known for its striking colors and euphoric effects.

• Studio 54 brings energetic and cerebral effects, often associated with bursts of creativity, focus, and social stimulation. It’s named after the legendary New York nightclub, and just like its namesake, it’s known to lift moods and keep the vibe electric.
• RS11, bred by Doja Pak, Deep East, and Wizard Trees, is a powerhouse strain with genetics rooted in Pink Guava and Sunset Sherbert. It’s famous for its sweet, fruity flavor and smooth, calming high that settles both body and mind.

When these two strains are crossed, Route 65 is born—delivering a synergy of mental stimulation and physical relaxation. The name “Route 65” alludes to a journey, much like the high itself, which takes you down a scenic road between alertness and tranquility.

Flavor Profile and Aroma

Route 65 is a sensory delight, offering a complex and mouth-watering flavor palette:

• Aroma: Upon opening a jar of Route 65, your senses are hit with an intoxicating mix of candy-like sweetness, diesel, and tropical fruit, underscored by hints of earthy pine and floral notes. There’s a sharp citrus tang that tickles the nose, followed by a creamy, almost pastry-like finish.
• Flavor: On the inhale, Route 65 delivers a blast of fruit punch, grape, and citrus zest, closely followed by a gassy backend and subtle hints of vanilla and herbal spice. It leaves a lingering sweetness on the tongue, making it a favorite for flavor-chasers and connoisseurs alike.

Its terpene profile likely includes Limonene, Caryophyllene, and Myrcene, giving it a balance of uplifting energy, anti-inflammatory effects, and deep relaxation.

Effects and Experience

What truly sets Route 65 apart is its balanced and adaptive high, making it ideal for various settings—whether you’re socializing with friends, tackling creative projects, or winding down after a long day.

Initial Effects: Users often report an immediate uplift in mood, with a clear-headed euphoria and a bubbly sense of joy. The Studio 54 genetics shine here, infusing the user with mental clarity, motivation, and a touch of artistic inspiration.

Mid-High: As the high progresses, the RS11 influence begins to mellow things out. A warm wave of physical relaxation takes over, soothing muscles and nerves without clouding the mind. This makes Route 65 perfect for daytime or early evening use—calming but not sedating.

Potential Benefits:

• Stress relief
• Creative flow
• Mild pain and inflammation reduction
• Social anxiety easing
• Mood elevation

Route 65 Cannabis in DC

In a crowded market of hybrid strains, Route 65 confidently carves its own lane. The combination of flavor-rich heritage, balanced effects, and modern breeding excellence makes this strain a must-try for cannabis enthusiasts.

It’s more than just another hybrid—it’s a journey of flavor, feeling, and freedom, inspired by two of the most revered strains in recent cannabis history. If you’re looking for a versatile, flavorful, and potent strain to elevate your cannabis experience, Route 65 is the road you want to travel. Check out our cannabis store in DC and our online menu for Route 65 Cannabis in DC.